Cash out to Neteller from PP or P* is usually very fast: except once, I can't remember when it took more than about 10 minutes. (I should note that I've never transferred more than $500 in or out of any site.) The one time it took longer, it was about 3 hours -- they sent an email notice saying they were reviewing my cashout. Don't know why -- I believe it was about $200, nothing huge. Seemed random. And as I said, only happened once.
It does, however, take longer to transfer funds from Neteller back to the bank account. That took about 3-4 days. There are options to make the transfer faster, but you pay extra for that. And transferring in to Neteller from my bank account is fast (but I don't remember exactly how long, but it was much faster than transferring back into the bank account).
Of course, as soon as you cashout money from any site, you will start to lose.

(Also known as the "cashout curse" -- another online-poker-is-rigged conspiracy myth that I absolutely don't believe.)